The GCGR Polyclonal Antibody is a valuable tool for researchers studying the Glucagon receptor (GCGR), a GPCR (G protein-coupled receptor) that plays a critical role in glucose homeostasis. This antibody, raised in rabbits, is highly specific to GCGR and is validated for use in various applications, including Western blotting and immunohistochemistry.GCGR is primarily expressed in the liver and pancreas and plays a key role in regulating glucose production and release. Dysregulation of GCGR signaling is associated with conditions such as diabetes and metabolic disorders, making it a promising target for therapeutic intervention.
The GCGR Polyclonal Antibody enables researchers to detect and analyze GCGR expression in different cell types and tissues, providing valuable insights into its function and potential as a therapeutic target. With its high specificity and sensitivity, this antibody is an essential tool for studies in diabetes research and metabolic disorders.
Product Name:
GCGR Rabbit Polyclonal Antibody
SKU:
CAB10617
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GCGR (NP_000151.1).
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).
Purification Method:
Affinity purification
Gene ID:
2642
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GCGR antibody (CAB10617) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
