Pro-glucagon Rabbit Polyclonal Antibody (CAB14609)
- SKU:
- CAB14609
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Pro-glucagon Rabbit Polyclonal Antibody |
SKU: | CAB14609 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-89 of human Pro-glucagon (NP_002045.1). |
Sequence: | RSLQ DTEE KSRS FSAS QADP LSDP DQMN EDKR HSQG TFTS DYSK YLDS RRAQ DFVQ WLMN TKRN RNNI A |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | GLP1; GLP2; GRPP; GLP-1; Pro-glucagon |
Positive Sample: | BxPC-3,293T,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 21kDa |
Observed MW: | 21kDa |
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Purification Method: | Affinity purification |
Gene ID: | 2641 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |