The GC Polyclonal Antibody (CAB5709) is a versatile tool for researchers studying the GC protein, which is involved in various physiological processes, including immune system regulation and inflammation. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications.The GC protein, also known as vitamin D-binding protein, plays a crucial role in vitamin D transport and metabolism, as well as in modulating immune responses. Studies have linked variations in GC protein levels to various diseases, making it an important target for research in autoimmune disorders, cancer, and metabolic diseases.
By targeting the GC protein, researchers can gain valuable insights into its function and potential therapeutic applications in various disease contexts. The GC Polyclonal Antibody (CAB5709) offers reliable detection and analysis of GC protein levels in different cell types, making it an invaluable tool for immunology and disease research.
Product Name:
GC Rabbit Polyclonal Antibody
SKU:
CAB5709
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 324-493 of human Vitamin D Binding protein (NP_001191236.1).
DBP; VDB; GRD3; VDBG; VDBP; GcMAF; DBP/GC; Gc-MAF; DBP-maf; HEL-S-51; Vitamin D Binding protein
Positive Sample:
Human serum,Mouse serum,THP-1
Conjugate:
Unconjugated
Cellular Localization:
Secreted.
Calculated MW:
53kDa
Observed MW:
60kDa
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2638
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Vitamin D Binding protein antibody (CAB5709) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
