null

GBP4 Antibody (PACO09427)

SKU:
PACO09427
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

GBP4 Antibody (PACO09427)

The GBP4 Antibody (PACO09427) is a polyclonal antibody specifically designed for research involving GBP4, a protein involved in immune responses and inflammation regulation. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blotting.GBP4 is a key player in the immune response, regulating inflammation and modulating immune function. Its role in immune regulation makes it a valuable target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.

Understanding the function of GBP4 is essential for developing therapies that can modulate immune responses effectively.The GBP4 Antibody (PACO09427) binds specifically to the GBP4 protein, enabling precise detection and analysis in various cell types. This makes it an ideal tool for studies in immunology, inflammation, and cancer research. By using this antibody, researchers can gain valuable insights into the role of GBP4 in immune regulation and potentially discover new targets for therapeutic intervention.

Antibody Name:GBP4 Antibody (PACO09427)
Antibody SKU:PACO09427
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human
Immunogen:Human GBP4
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:guanylate binding protein 4;GBP4;Mpa2 ;
UniProt Protein Function:GBP4: Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation. Belongs to the GBP family.
UniProt Protein Details:

Protein type:Cell adhesion; Hydrolase; Vesicle

Chromosomal Location of Human Ortholog: 1p22.2

Cellular Component: Golgi membrane; nucleus; perinuclear region of cytoplasm

Molecular Function:GTP binding; GTPase activity

Biological Process: metabolic process

NCBI Summary:Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008]
UniProt Code:Q96PP9
NCBI GenInfo Identifier:116242487
NCBI Gene ID:115361
NCBI Accession:Q96PP9.2
UniProt Secondary Accession:Q96PP9,Q05D63, Q6NSL0, Q86T99, B2R630,
UniProt Related Accession:Q96PP9
Molecular Weight:73,165 Da
NCBI Full Name:Guanylate-binding protein 4
NCBI Synonym Full Names:guanylate binding protein 4
NCBI Official Symbol:GBP4  
NCBI Official Synonym Symbols:Mpa2  
NCBI Protein Information:guanylate-binding protein 4
UniProt Protein Name:Guanylate-binding protein 4
UniProt Synonym Protein Names:GTP-binding protein 4; GBP-4; Guanine nucleotide-binding protein 4
Protein Family:Guanylate-binding protein
UniProt Gene Name:GBP4  
UniProt Entry Name:GBP4_HUMAN

Related Products