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GBP4 Antibody (PACO02432)

SKU:
PACO02432
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269

Description

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GBP4 Antibody (PACO02432)

The GBP4 Antibody (PACO02432) is a polyclonal antibody designed for research involving GBP4, a member of the guanylate-binding protein family known for its role in immune defense and inflammation. The antibody is generated in rabbits and exhibits high reactivity with human samples, making it an excellent tool for studying GBP4 in various research applications.GBP4 is a key player in the innate immune response, particularly in the defense against viral and bacterial infections. Its ability to modulate inflammatory processes and regulate immune activation makes it a promising target for investigating immune-related disorders and developing therapeutic interventions.

This antibody is validated for use in Western blot applications, enabling researchers to detect and analyze GBP4 protein expression in different cell types. Its specificity and reliability make it an essential tool for studies in immunology, infectious diseases, and inflammation research. By understanding the function of GBP4, researchers can gain valuable insights into the immune response mechanisms and potentially develop new strategies for treating immune-related disorders.

Antibody Name:GBP4 Antibody
Antibody SKU:PACO02432
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:Human
Immunogen:synthesized peptide derived from the C-terminal region of human GBP4.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:GBP4; Guanylate-binding protein 4; GTP-binding protein 4; GBP-4; Guanine nucleotide-binding protein 4
UniProt Protein Function:GBP4: Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation. Belongs to the GBP family.
UniProt Protein Details:

Protein type:Cell adhesion; Hydrolase; Vesicle

Chromosomal Location of Human Ortholog: 1p22.2

Cellular Component: Golgi membrane; nucleus; perinuclear region of cytoplasm

Molecular Function:GTP binding; GTPase activity

Biological Process: metabolic process

NCBI Summary:Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008]
UniProt Code:Q96PP9
NCBI GenInfo Identifier:116242487
NCBI Gene ID:115361
NCBI Accession:Q96PP9.2
UniProt Secondary Accession:Q96PP9,Q05D63, Q6NSL0, Q86T99, B2R630,
UniProt Related Accession:Q96PP9
Molecular Weight:73,165 Da
NCBI Full Name:Guanylate-binding protein 4
NCBI Synonym Full Names:guanylate binding protein 4
NCBI Official Symbol:GBP4  
NCBI Official Synonym Symbols:Mpa2  
NCBI Protein Information:guanylate-binding protein 4
UniProt Protein Name:Guanylate-binding protein 4
UniProt Synonym Protein Names:GTP-binding protein 4; GBP-4; Guanine nucleotide-binding protein 4
Protein Family:Guanylate-binding protein
UniProt Gene Name:GBP4  
UniProt Entry Name:GBP4_HUMAN

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