The GBP2 Polyclonal Antibody (CAB12994) is a valuable tool for researchers studying GBP2, a protein involved in immune regulation and antiviral defense mechanisms. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By binding to the GBP2 protein, this antibody enables the detection and analysis of GBP2 in various cell types, making it particularly useful for studies in immunology and virology research.GBP2, also known as Guanylate Binding Protein 2, plays a critical role in the innate immune response to viral infections by inhibiting virus replication and promoting antiviral immune responses.
Its importance in host defense against viral pathogens makes it a promising target for research on viral diseases and antiviral therapies. Understanding the function of GBP2 is essential for developing strategies to enhance the immune response to viruses and potentially treat viral infections more effectively.
Product Name:
GBP2 Rabbit Polyclonal Antibody
SKU:
CAB12994
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 410-520 of human GBP2 (NP_004111.2).
This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas.
Purification Method:
Affinity purification
Gene ID:
2634
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GBP2 Rabbit pAb (CAB12994) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
