The GBF1 Polyclonal Antibody (CAB12539) is a valuable tool for researchers studying GBF1, a protein involved in regulating membrane traffic in cells. This antibody, produced by Assay Genie, is raised in rabbits and is highly specific for detecting GBF1 in human samples. Validated for use in Western blot applications, this antibody binds to GBF1, allowing for accurate detection and analysis in a variety of cell types.GBF1, also known as ARF-GEF1, plays a crucial role in regulating the transport of proteins and lipids within cells, making it essential for maintaining cellular functions and organelle integrity.
Dysfunction of GBF1 has been linked to various diseases, including neurological disorders and certain types of cancer. By studying GBF1 and its functions, researchers can gain insights into disease mechanisms and potential therapeutic targets.Overall, the GBF1 Polyclonal Antibody (CAB12539) is an essential tool for researchers interested in unraveling the complex roles of GBF1 in cellular processes and disease development. Its high specificity and sensitivity make it ideal for use in immunology, cancer research, and cell biology studies.
Product Name:
GBF1 Rabbit Polyclonal Antibody
SKU:
CAB12539
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human GBF1 (NP_004184.1).
This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
8729
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using GBF1 Antibody (CAB12539) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
