GBE1 Rabbit Polyclonal Antibody (CAB6599)
- SKU:
- CAB6599
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | GBE1 Rabbit Polyclonal Antibody |
SKU: | CAB6599 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GBE1 (NP_000149.3). |
Sequence: | MAAP MTPA ARPE DYEA ALNA ALAD VPEL ARLL EIDP YLKP YAVD FQRR YKQF SQIL KNIG ENEG GIDK FSRG YESF GVHR CADG GLYC KEWA PGAE GVFL TGDF NGWN PFSY PYKK LDYG KWEL YIPP KQNK SVLV PHGS KLKV VITS KSGE ILYR ISPW AKYV VREG DNVN YDWI HWDP EHSY EFKH SRPK KPRS LRIY ESHV GISS HEGK VASY KHFT CNVL PRIK GLGY NCIQ LMAI MEHA YYAS FGYQ ITSF FAAS SRYG TPEE LQEL VDTA HSMG IIVL LDVV HSHA SKNS ADGL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GBE; APBD; GSD4; GBE1 |
Positive Sample: | HepG2,NCI-H460,Mouse heart,Mouse liver,Mouse kidney,Rat liver,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, extracellular exosome |
Calculated MW: | 80kDa |
Observed MW: | 80kDa |
The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease).
Purification Method: | Affinity purification |
Gene ID: | 2632 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |