The GBA2 Polyclonal Antibody (CAB12834) is a vital tool for researchers studying GBA2, a key enzyme involved in the metabolism of lipids and the regulation of cellular processes. This antibody, raised in rabbits, exhibits high reactivity towards human samples and is validated for use in Western blot applications. By binding specifically to the GBA2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential resource for studies in biochemistry and molecular biology.GBA2, also known as glucocerebrosidase 2, plays a crucial role in maintaining lipid homeostasis and cellular function.
Dysregulation of GBA2 has been implicated in various diseases, including neurodegenerative disorders and metabolic syndromes. Investigating the functions of GBA2 is essential for understanding its potential implications in disease pathogenesis and developing targeted therapies. The GBA2 Polyclonal Antibody offers researchers a valuable tool to explore the biological role of GBA2 and its involvement in health and disease.
Product Name:
GBA2 Rabbit Polyclonal Antibody
SKU:
CAB12834
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 708-927 of human GBA2 (NP_065995.1).
This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism.
Purification Method:
Affinity purification
Gene ID:
57704
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GBA2 Rabbit pAb (CAB12834) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
