Glucosylceramidase beta (GBA) Rabbit Monoclonal Antibody (CAB19057)
- SKU:
- CAB19057
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | Glucosylceramidase beta (GBA) Rabbit Monoclonal Antibody |
SKU: | CAB19057 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 437-536 of human Glucosylceramidase beta (GBA) (P04062). |
Sequence: | VDSP IIVD ITKD TFYK QPMF YHLG HFSK FIPE GSQR VGLV ASQK NDLD AVAL MHPD GSAV VVVL NRSS KDVP LTIK DPAV GFLE TISP GYSI HTYL WRRQ |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | GBA; GCB; GLUC; Glucosylceramidase beta (GBA) |
Positive Sample: | SH-SY5Y,MCF7,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Lumenal side, Lysosome membrane, Peripheral membrane protein. |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2629 |
Clone Number: | ARC0500 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |