GATM Rabbit Polyclonal Antibody (CAB6598)
- SKU:
- CAB6598
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GATM Rabbit Polyclonal Antibody |
SKU: | CAB6598 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 38-423 of human GATM (NP_001473.1?). |
Sequence: | STQA ATAS SRNS CAAD DKAT EPLP KDCP VSSY NEWD PLEE VIVG RAEN ACVP PFTI EVKA NTYE KYWP FYQK QGGH YFPK DHLK KAVA EIEE MCNI LKTE GVTV RRPD PIDW SLKY KTPD FEST GLYS AMPR DILI VVGN EIIE APMA WRSR FFEY RAYR SIIK DYFH RGAK WTTA PKPT MADE LYNQ DYPI HSVE DRHK LAAQ GKFV TTEF EPCF DAAD FIRA GRDI FAQR SQVT NYLG IEWM RRHL APDY RVHI ISFK DPNP MHID ATFN IIGP GIVL SNPD RPCH QIDL FKKA GWTI ITPP TPII PDDH PLWM SSKW LSMN VLML DEKR VMVD ANEV PIQK MFEK LGIT TIKV NIRN ANSL GGGF HCWT CDVR RRGT LQSY LD |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | AT; RFS; AGAT; FRTS; CCDS3; FRTS1; GATM |
Positive Sample: | U-251MG,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Intermembrane side, Mitochondrion inner membrane, Peripheral membrane protein. |
Calculated MW: | 48kDa |
Observed MW: | 48kDa |
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by cognitive disability, language impairment, and behavioral disorders.
Purification Method: | Affinity purification |
Gene ID: | 2628 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |