The GATC Polyclonal Antibody (CAB8604) is an essential tool for researchers studying GATC, a key enzyme involved in DNA replication and repair processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications. By binding to the GATC protein, researchers can easily detect and analyze its expression levels in various cell types, facilitating investigations in fields such as genomics, molecular biology, and cancer research.GATC, a crucial component of the DNA methylation cycle, plays a pivotal role in maintaining genomic integrity and stability.
Dysregulation of GATC expression has been linked to various diseases, including cancer and genetic disorders. Therefore, detailed understanding of GATC function is essential for developing targeted therapies and diagnostic tools for these conditions. The GATC Polyclonal Antibody (CAB8604) provides researchers with a valuable resource for elucidating the role of GATC in cellular processes and disease pathogenesis.
Product Name:
GATC Rabbit Polyclonal Antibody
SKU:
CAB8604
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human GATC (NP_789788.1).
Enables glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Located in mitochondrion. Part of glutamyl-tRNA(Gln) amidotransferase complex. Implicated in combined oxidative phosphorylation deficiency 42.
Purification Method:
Affinity purification
Gene ID:
283459
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GATC antibody (CAB8604) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
