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GATAD2A Antibody (PACO57284)

SKU:
PACO57284
Product Type:
Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • GATAD2A Antibody PACO57284
  • GATAD2A Antibody PACO57284
  • GATAD2A Antibody PACO57284
€359

Description

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GATAD2A Antibody (PACO57284)

The GATAD2A Polyclonal Antibody (PAC057284) is a valuable tool for research involving GATAD2A, a protein involved in chromatin remodeling and gene regulation. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. It binds to the GATAD2A protein, allowing for accurate detection and analysis in various cell types.GATAD2A is known to interact with various transcription factors and chromatin-modifying enzymes, playing a crucial role in the regulation of gene expression.

Its involvement in chromatin remodeling processes makes it a key player in cellular development and differentiation. Research on GATAD2A is important for understanding its role in various biological processes and its implications in diseases such as cancer and developmental disorders.Overall, the GATAD2A Polyclonal Antibody is a reliable tool for studying the function and regulation of GATAD2A in different cellular contexts, providing valuable insights for researchers in the fields of chromatin biology and gene regulation.

Antibody Name:GATAD2A Antibody (PACO57284)
Antibody SKU:PACO57284
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:500-1:1000
Species Reactivity:Human, Rat
Immunogen:Recombinant Human Transcriptional repressor p66-α protein (170-241AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern Blot. Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate, 293 whole cell lysate, HL60 whole cell lysate, MCF-7 whole cell lysate, Rat stomach tissue. All lanes: GATAD2A antibody at 2.9µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 69, 66 kDa. Observed band size: 69 kDa.
Product ImageIHC image of PACO57284 diluted at 1:800 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Product ImageIHC image of PACO57284 diluted at 1:800 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2B.
Synonyms:Transcriptional repressor p66-α (Hp66alpha) (GATA zinc finger domain-containing protein 2A), GATAD2A
UniProt Protein Function:GATAD2A: Transcriptional repressor. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 19p13.11Cellular Component: nucleoplasm; nuclear speck; NuRD complex; nucleusMolecular Function: protein binding, bridging; protein binding; zinc ion binding; sequence-specific DNA binding; transcription factor activityBiological Process: blood vessel development; embryonic body morphogenesis; neural fold formation; transcription, DNA-dependent; anterior neuropore closure; in utero embryonic development; DNA methylation; programmed cell death; negative regulation of transcription, DNA-dependent
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q86YP4
NCBI GenInfo Identifier:164519146
NCBI Gene ID:54815
NCBI Accession:NP_060130.3
UniProt Secondary Accession:Q86YP4
UniProt Related Accession:Q86YP4
Molecular Weight:
NCBI Full Name:transcriptional repressor p66-alpha isoform 2
NCBI Synonym Full Names:GATA zinc finger domain containing 2A
NCBI Official Symbol:GATAD2A  
NCBI Official Synonym Symbols:p66alpha  
NCBI Protein Information:transcriptional repressor p66-alpha
UniProt Protein Name:Transcriptional repressor p66-alpha
UniProt Synonym Protein Names:GATA zinc finger domain-containing protein 2A
Protein Family:Transcriptional repressor
UniProt Gene Name:GATAD2A  
UniProt Entry Name:P66A_HUMAN
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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