The GATA6 Polyclonal Antibody (CAB16634) is a powerful tool for researchers studying the GATA6 protein, a transcription factor involved in the regulation of gene expression and cell differentiation. The antibody, produced in rabbits, has been extensively validated for use in various applications, including Western blotting and immunofluorescence.GATA6 is known for its role in organ development, specifically in the formation of the heart, lungs, and pancreas. Dysregulation of GATA6 has been associated with various diseases, including cardiac defects, pulmonary disorders, and pancreatic cancer. By targeting GATA6 with this antibody, researchers can investigate its expression levels and localization in different cell types, providing valuable insights into its function and potential implications in disease pathology.
With its high specificity and sensitivity, the GATA6 Polyclonal Antibody is a valuable tool for studying the intricate mechanisms of gene regulation and cell differentiation. Its application extends to various areas of research, including developmental biology, cancer biology, and regenerative medicine, making it an essential component in advancing our understanding of GATA6 biology.
Product Name:
GATA6 Rabbit Polyclonal Antibody
SKU:
CAB16634
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 70-160 of human GATA6 (NP_005248.2).
This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects.
Purification Method:
Affinity purification
Gene ID:
2627
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using (CAB16634) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
