The GATA3 Rabbit Monoclonal Antibody (CAB19636) is a cutting-edge tool for research on GATA3, a transcription factor that plays a key role in the development and differentiation of T-cells, as well as in the regulation of Th2 cell-mediated immune responses. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for various research applications, including Western blotting.GATA3 is essential for the development and function of Th2 cells, making it a crucial target for studies in immunology, allergy, and asthma research. By binding to the GATA3 protein, this antibody enables accurate detection and analysis in various cell types, allowing researchers to further explore the mechanisms underlying immune responses and inflammatory conditions.
Its reliability and performance make it an invaluable tool for unraveling the complexities of immune regulation and developing potential therapies for related diseases.Overall, the GATA3 Rabbit Monoclonal Antibody (CAB19636) offers a powerful means to investigate the role of GATA3 in immune modulation and disease pathology, providing researchers with a valuable resource for advancing their studies in immunology and related fields.
Product Name:
GATA3 Rabbit Monoclonal Antibody
SKU:
CAB19636
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GATA3 (P23771).
WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsChIP,5μg antibody for 10μg-15μg of ChromatinChIP-seq,1:50 - 1:100
Synonyms:
HDR; HDRS; GATA3
Positive Sample:
SH-SY5Y,MCF7
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
48kDa
Observed MW:
48kDa
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
Purification Method:
Affinity purification
Gene ID:
2625
Clone Number:
ARC0115
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Chromatin immunoprecipitations were performed with cross-linked chromatin from 293T cells transfected with GATA3 and GATA3 (CAB19636). The ChIP sequencing results indicate the enrichment pattern of GATA3 in selected genomic region and representative gene loci (SH3RF3), as shown in figure.
