The GATA3 Polyclonal Antibody (CAB10216) is specially designed for researchers studying the GATA3 protein, a transcription factor that plays a crucial role in T cell development and differentiation. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications such as Western blotting and immunohistochemistry.GATA3 is known for its involvement in regulating gene expression in T cells, particularly in the differentiation of Th2 cells and the production of cytokines involved in allergic responses.
Its role in immune regulation and its implications in diseases like asthma and allergic disorders make it a key target for research in immunology and respiratory medicine.By utilizing the GATA3 Polyclonal Antibody, researchers can accurately detect and analyze the levels of GATA3 protein in different cell types, providing valuable insights into the mechanisms underlying immune responses and potential therapeutic targets for immune-related disorders. This antibody proves to be a valuable tool for studies focusing on T cell biology, allergy, and autoimmune diseases.
Product Name:
GATA3 Polyclonal Antibody
SKU:
CAB21809
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GATA3 (NP_001002295.1).
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
Purification Method:
Affinity purification
Gene ID:
2625
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of Mouse brain, using GATA3 Rabbit pAb (CAB21809) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
