The GATA3 Polyclonal Antibody (CAB1638) offered by Assay Genie is a valuable tool for researchers studying GATA3, a critical transcription factor involved in the differentiation and function of T cells and other immune cells. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.GATA3 plays a vital role in immune system regulation, particularly in the development and function of T helper 2 (Th2) cells. Dysregulation of GATA3 has been implicated in various diseases, including asthma, allergies, and certain types of cancer.
The GATA3 Polyclonal Antibody enables researchers to detect and analyze GATA3 expression in different cell types, aiding in studies related to immunology and cancer research.By understanding the function of GATA3, researchers can gain insights into the molecular mechanisms underlying immune responses and potentially identify new therapeutic targets for immune-related disorders. The GATA3 Polyclonal Antibody is a valuable tool for elucidating the role of GATA3 in health and disease, making it a valuable asset for immunology research.
Product Name:
GATA3 Rabbit Polyclonal Antibody
SKU:
CAB1638
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GATA3 (NP_001002295.1).
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
Purification Method:
Affinity purification
Gene ID:
2625
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts from normal (control) and GATA3 knockout (KO) 293T cells, using GATA3 antibody (CAB1638) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
