The GATA1 Polyclonal Antibody (CAB0475) is a crucial tool for researchers studying GATA1, a transcription factor essential for normal erythroid and megakaryocytic development. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the GATA1 protein, this antibody allows for accurate detection and analysis in various cell types, making it an ideal choice for studies in hematology and developmental biology.GATA1 is a key regulator of hematopoiesis, playing a critical role in the differentiation of red blood cells and platelets.
Dysregulation of GATA1 expression has been implicated in various blood disorders, including leukemia and anemia. Therefore, understanding the function and activity of GATA1 is essential for furthering research into these conditions and developing targeted therapies.Overall, the GATA1 Polyclonal Antibody is a valuable tool for researchers investigating hematopoiesis and blood disorders, providing reliable and accurate detection of GATA1 protein levels in various experimental contexts.
Product Name:
GATA1 Rabbit Polyclonal Antibody
SKU:
CAB0475
Size:
100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 55-155 of human GATA1 (NP_002040.1).
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.
Purification Method:
Affinity purification
Gene ID:
2623
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from NIH/3T3 cells, using GATA1 Rabbit pAb (CAB0475).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
