The GAST Polyclonal Antibody (CAB14571) is a valuable tool for researchers studying GAST, a protein involved in the regulation of gastric acid secretion and mucosal defense in the stomach. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it ideal for use in various immunoassays and immunohistochemistry applications.GAST, also known as gastrin, is a peptide hormone that plays a crucial role in stimulating gastric acid secretion and maintaining the integrity of the gastric mucosa.
Dysregulation of GAST expression has been linked to various gastric disorders, including gastric cancer and peptic ulcers. By utilizing the GAST Polyclonal Antibody, researchers can investigate the function and expression of GAST in different cell types and tissues, furthering our understanding of its role in gastric physiology and pathology.
Product Name:
GAST Rabbit Polyclonal Antibody
SKU:
CAB14571
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GAST (NP_000796.1).
Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17.
Purification Method:
Affinity purification
Gene ID:
2520
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse stomach, using GAST Rabbit pAb (CAB14571) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
