Anti-GAS8 Antibody (PACO19696)

Antibody Name:	GAS8 Antibody (PACO19696)
Antibody SKU:	PACO19696
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide of human GAS8

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO19696(GAS8 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19696(GAS8 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:	This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms:	growth arrest-specific 8

UniProt Protein Function:	GAS8: Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility. Belongs to the GAS8 family.Protein type: CytoskeletalChromosomal Location of Human Ortholog: 16q24.3Cellular Component: Golgi apparatus; microtubuleMolecular Function: Rab GTPase bindingBiological Process: negative regulation of cell proliferation; sperm motility
UniProt Protein Details:
NCBI Summary:	This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
UniProt Code:	O95995
NCBI GenInfo Identifier:	555290160
NCBI Gene ID:	2622
NCBI Accession:	NP_001273134.1
UniProt Secondary Accession:	O95995,Q2M234, B2RCT1, B7Z4U1, G3V1L5
UniProt Related Accession:	O95995
Molecular Weight:	53,809 Da
NCBI Full Name:	growth arrest-specific protein 8 isoform b
NCBI Synonym Full Names:	growth arrest-specific 8
NCBI Official Symbol:	GAS8
NCBI Official Synonym Symbols:	GAS11
NCBI Protein Information:	growth arrest-specific protein 8
UniProt Protein Name:	Growth arrest-specific protein 8
UniProt Synonym Protein Names:	Growth arrest-specific protein 11; GAS-11
Protein Family:	Growth arrest-specific protein
UniProt Gene Name:	GAS8
UniProt Entry Name:	GAS8_HUMAN

Antibodies

GAS8 Antibody (PACO03824)

GAS8 Antibody (PACO09417)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)