The GARS Rabbit Monoclonal Antibody is an essential tool for researchers studying GARS, a key enzyme involved in aminoacylation of tRNA and protein synthesis. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards GARS protein, enabling accurate detection and quantification in various biological samples.GARS, also known as glycyl-tRNA synthetase, is vital for protein translation and plays a crucial role in maintaining cellular functions. Dysregulation of GARS has been linked to various neurological disorders, making it a promising target for therapeutic interventions. By utilizing the GARS Rabbit Monoclonal Antibody, researchers can delve deeper into the mechanisms underlying these diseases and develop targeted therapies to address them effectively.
This antibody is validated for use in Western blot assays, immunofluorescence, and immunohistochemistry, providing versatility for researchers in molecular biology, neuroscience, and drug discovery. Its high affinity and specificity make it a valuable tool for elucidating the role of GARS in normal cellular processes and disease pathogenesis. Get your hands on the GARS Rabbit Monoclonal Antibody today and advance your research in protein synthesis and neurological disorders.
Product Name:
GARS Rabbit Monoclonal Antibody
SKU:
CAB0651
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 640-739 of human GARS (P41250).
This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2617
Clone Number:
ARC0514
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of Jurkat, using GARS antibody (CAB0651) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
