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GARS Monoclonal Antibody [PAT4E10AT] (CPAB0191)

SKU:
CPAB0191
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT4E10AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

GARS Monoclonal Antibody [PAT4E10AT] (CPAB0191)

The GARS Polyclonal Antibody (CPAB0191) is a valuable tool for researchers studying GARS, a key enzyme involved in aminoacylation of transfer RNA. This antibody, produced in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples. It binds to the GARS protein, allowing for accurate detection and analysis in a variety of cell types.GARS is essential for protein synthesis and cell growth, making it a crucial target for research in molecular biology and genetic disorders.

Mutations in GARS have been linked to various neurological disorders and diseases, making it essential to study its function and regulation. The GARS Polyclonal Antibody is an essential tool for researchers investigating the role of GARS in health and disease, aiding in the development of potential therapies and treatments.

Product Name:GARS Antibody
Product Sku:CPAB0191
Size:5μg
Host Species:Mouse
Immunogen:Anti-human GARS mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GARS amino acids 43-289 purified from Ecoli.
Clone:PAT4E10AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:GARS antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:GARS is an (alpha)2 dimer which is a member of the class II family of tRNA synthetases. GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases which charge tRNAs with their cognate amino acids. GARS catalyzes the attachment of glycine to tRNA(Gly). In addition, GARS is able to produce diadenosine tetraphosphate (Ap4A), which is a universal pleiotropic signaling molecule required for cell regulation pathways, by direct condensation of two ATPs. GARS has been demonstrated to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Synonyms:Glycine--tRNA ligase, Diadenosine tetraphosphate synthetase, AP-4-A synthetase, Glycyl-tRNA synthetase, GlyRS, GARS, CMT2D, DSMAV, HMN5, SMAD1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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