GAR1 Rabbit Polyclonal Antibody (CAB12748)
- SKU:
- CAB12748
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | GAR1 Rabbit Polyclonal Antibody |
SKU: | CAB12748 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-170 of human GAR1 (NP_061856.1). |
Sequence: | KGQD QGPP ERVV LLGE FLHP CEDD IVCK CTTD ENKV PYFN APVY LENK EQIG KVDE IFGQ LRDF YFSV KLSE NMKA SSFK KLQK FYID PYKL LPLQ RFLP RPPG EKGP PRG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | NOLA1; GAR1 |
Positive Sample: | Mouse kidney,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cajal body, Nucleus, nucleolus. |
Calculated MW: | 22kDa |
Observed MW: | 28kDa |
This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p. Two splice variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 54433 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |