The GAP43 Polyclonal Antibody (CAB16857) is specifically designed for research involving GAP43, a protein crucial for neuronal development and regeneration. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blot, immunofluorescence, and immunohistochemistry.GAP43, also known as Growth-Associated Protein 43, is a key player in neuronal plasticity and axonal growth. Its expression is upregulated in response to nerve damage, making it a marker for neuroregeneration.
By targeting GAP43 with this antibody, researchers can investigate its role in neurodevelopment, injury recovery, and neurodegenerative diseases.With its ability to detect GAP43 in different cell types and tissues, this polyclonal antibody is an invaluable tool for studies in neuroscience, neurology, and regenerative medicine. Understanding the functions of GAP43 could lead to new insights and potential therapeutic strategies for neurological conditions and injuries.
Product Name:
GAP43 Rabbit Polyclonal Antibody
SKU:
CAB16857
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-238 of human GAP43 (NP_002036.1).
The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2596
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GAP43 Rabbit pAb (CAB16857) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
