The GANC Polyclonal Antibody (CAB16377) is a versatile tool for researchers studying GANC, a protein involved in cell growth and differentiation processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the GANC protein, this antibody allows for the accurate detection and analysis of GANC expression in various cell types.GANC, also known as glucosamine-6-phosphate N-acetyltransferase, is a key enzyme in the biosynthesis of glucosamine-6-phosphate, a precursor for the synthesis of important cellular components like glycosaminoglycans and glycolipids.
Dysregulation of GANC has been implicated in various diseases, including cancer and metabolic disorders. Studying the role of GANC in these conditions could provide valuable insights for the development of targeted therapies.Overall, the GANC Polyclonal Antibody (CAB16377) is a valuable tool for researchers interested in unraveling the complex mechanisms involving GANC and its implications in human health and disease. Its high specificity and sensitivity make it an essential component for investigations in molecular biology, biochemistry, and biomedical research.
Product Name:
GANC Rabbit Polyclonal Antibody
SKU:
CAB16377
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human GANC (NP_937784.2).
Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
2595
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GANC Rabbit pAb (CAB16377) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
