GAMT Rabbit Polyclonal Antibody (CAB6597)
- SKU:
- CAB6597
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GAMT Rabbit Polyclonal Antibody |
SKU: | CAB6597 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human GAMT (NP_000147.1). |
Sequence: | MSAP SATP IFAP GENC SPAW GAAP AAYD AADT HLRI LGKP VMER WETP YMHA LAAA ASSK GGRV LEVG FGMA IAAS KVQE APID EHWI IECN DGVF QRLR DWAP RQTH KVIP LKGL WEDV APTL PDGH FDGI LYDT YPLS EETW HTHQ FNFI KNHA FRLL KPGG VLTY CNLT SWGE LMKS KYSD ITIM FEET QVPA LLEA GFRR ENIR TEVM ALVP PADC RYYA FPQM ITPL VTKG |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | PIG2; CCDS2; TP53I2; HEL-S-20; GAMT |
Positive Sample: | HepG2,Jurkat,HeLa,293T,Mouse liver,Rat liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, nucleus |
Calculated MW: | 26kDa |
Observed MW: | 29kDa |
The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.
Purification Method: | Affinity purification |
Gene ID: | 2593 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |