GALT Polyclonal Antibody (CAB21426)
- SKU:
- CAB21426
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | GALT Polyclonal Antibody |
SKU: | CAB21426 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-379 of human GALT (NP_000146.2). |
Sequence: | MSRS GTDP QQRQ QASE ADAA AATF RAND HQHI RYNP LQDE WVLV SAHR MKRP WQGQ VEPQ LLKT VPRH DPLN PLCP GAIR ANGE VNPQ YDST FLFD NDFP ALQP DAPS PGPS DHPL FQAK SARG VCKV MCFH PWSD VTLP LMSV PEIR AVVD AWAS VTEE LGAQ YPWV QIFE NKGA MMGC SNPH PHCQ VWAS SFLP DIAQ REER SQQA YKSQ HGEP LLME YSRQ ELLR KERL VLTS EHWL VLVP FWAT WPYQ TLLL PRRH VRRL PELT PAER DDLA SIMK KLLT KYDN LFET SFPY SMGW HGAP TGSE AGAN WNHW QLHA HYYP PLLR SATV RKFM VGYE MLAQ AQRD LTPE QAAE RLRA LPEV HYHL GQKD RETA TIA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GALT; galactose-1-phosphate uridylyltransferase |
Positive Sample: | SK-OV-3,THP-1,Hep G2,Mouse liver,Mouse kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, Golgi apparatus |
Calculated MW: | 43kDa |
Observed MW: | Refer to figures |
Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2592 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |