GALNT6 Rabbit Polyclonal Antibody (CAB14853)
- SKU:
- CAB14853
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | GALNT6 Rabbit Polyclonal Antibody |
SKU: | CAB14853 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-140 of human GALNT6 (NP_009141.2). |
Sequence: | DVSS REEA TEKP WLKS LVSR KDHV LDLM LEAM NNLR DSMP KLQI RAPE AQQT LFSI NQSC LPGF YTPA ELKP FWER PPQD PNAP GADG KAFQ KSKW TPLE TQEK EEGY KKH |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GalNAcT6; GALNAC-T6; GALNT6 |
Positive Sample: | U-87MG,BxPC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus membrane, Single-pass type II membrane protein. |
Calculated MW: | 71kDa |
Observed MW: | 71kDa |
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin.
Purification Method: | Affinity purification |
Gene ID: | 11226 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |