The GALNT3 Polyclonal Antibody (CAB6596) is a valuable tool for researchers studying GALNT3, a protein involved in the glycosylation of proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the GALNT3 protein, researchers can easily detect and analyze its expression in various cell types, making it ideal for studies in glycobiology and cancer research.GALNT3, also known as UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3, plays a crucial role in the glycosylation process, which impacts numerous cellular functions.
Understanding the role of GALNT3 in protein glycosylation is essential for uncovering its involvement in diseases such as cancer, diabetes, and genetic disorders. By investigating the function of GALNT3, researchers can gain insights into potential therapeutic targets for these conditions.
Product Name:
GALNT3 Rabbit Polyclonal Antibody
SKU:
CAB6596
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human GALNT3 (NP_004473.2).
Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein.
Calculated MW:
73kDa
Observed MW:
73kDa
This gene encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein encoded by this gene is highly homologous to other family members, however the enzymes have different substrate specificities.
Purification Method:
Affinity purification
Gene ID:
2591
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GALNT3 antibody (CAB6596) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
