The GALNT3 Polyclonal Antibody (CAB13985) is a valuable tool for researchers studying GALNT3, a glycosyltransferase enzyme involved in the post-translational glycosylation of proteins. This antibody, derived from rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.GALNT3 plays a key role in the glycosylation process by adding N-acetylgalactosamine (GalNAc) to target proteins, thereby influencing their structure and function. Dysregulation of GALNT3 has been implicated in various diseases, including cancer and metabolic disorders, making it a promising target for therapeutic intervention.
By detecting the presence of GALNT3 in different cell types, this antibody enables researchers to investigate the function and regulation of this enzyme in normal biological processes and disease states. Its specificity and sensitivity make it an essential tool for advancing our understanding of glycosylation pathways and their implications in health and disease.
Product Name:
GALNT3 Rabbit Polyclonal Antibody
SKU:
CAB13985
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 43-160 of human GALNT3 (NP_004473.2).
Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein.
Calculated MW:
73kDa
Observed MW:
73kDa
This gene encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein encoded by this gene is highly homologous to other family members, however the enzymes have different substrate specificities.
Purification Method:
Affinity purification
Gene ID:
2591
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GALNT3 Rabbit pAb (CAB13985) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
