The GALNT2 Polyclonal Antibody (CAB6910) is a valuable tool for researchers studying GALNT2, a protein involved in glycosylation processes in cells. This antibody, generated in rabbits, shows high specificity for human samples and has been validated for use in Western blot applications. By binding to the GALNT2 protein, researchers can easily detect and analyze its expression in various cell types, making it an ideal choice for studies in glycobiology and cancer research.
GALNT2 is a key enzyme in the glycosylation pathway, responsible for adding sugar molecules to proteins to modify their function. Dysregulation of GALNT2 has been implicated in cancer progression and metastasis, making it a promising target for therapeutic interventions. By understanding the role of GALNT2 in glycosylation, researchers can develop novel strategies for treating cancer and other diseases with aberrant glycosylation patterns.
Product Name:
GALNT2 Rabbit Polyclonal Antibody
SKU:
CAB6910
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 442-571 of human GALNT2 (NP_004472.1).
Golgi apparatus, Golgi stack membrane, Secreted, Single-pass type II membrane protein.
Calculated MW:
65kDa
Observed MW:
65kDa
This gene encodes a member of the glycosyltransferase 2 protein family. Members of this family initiate mucin-type O-glycoslation of peptides in the Golgi apparatus. The encoded protein may be involved in O-linked glycosylation of the immunoglobulin A1 hinge region. This gene may influence triglyceride levels, and may be involved Type 2 diabetes, as well as several types of cancer. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2590
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GALNT2 Rabbit pAb (CAB6910) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
