null

GALNT15 Antibody (PACO38246)

SKU:
PACO38246
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • GALNT15 Antibody PACO38246
  • GALNT15 Antibody PACO38246
€339

Description

system_update_altDatasheetsystem_update_altMSDS

GALNT15 Antibody (PACO38246)

The GALNT15 Antibody (PAC038246) is a valuable tool for researchers studying GALNT15, a glycosyltransferase enzyme involved in protein glycosylation processes. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in various applications, including Western blotting. By binding to the GALNT15 protein, this antibody enables efficient detection and analysis in different cell types, making it an ideal choice for studies in glycobiology and cancer research.GALNT15 plays a crucial role in protein glycosylation, a post-translational modification essential for cellular functions such as cell adhesion, signaling, and immune response regulation.

Dysregulation of GALNT15 has been implicated in various diseases, including cancer and inflammatory disorders, highlighting its potential as a therapeutic target. Further research into the functions of GALNT15 is key to understanding its impact on disease development and progression, paving the way for the development of novel treatments targeting glycosylation pathways.

Antibody Name:GALNT15 Antibody (PACO38246)
Antibody SKU:PACO38246
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200
Species Reactivity:Human, Mouse
Immunogen:Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 15 protein (35-335AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern blot. All lanes: GALNT15 antibody at 5µg/ml. Lane 1: Mouse liver tissue. Lane 2: Mouse kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 74 kDa. Observed band size: 74 kDa.
Product ImageImmunohistochemistry of paraffin-embedded human kidney tissue using PACO38246 at dilution of 1:100.
Background:Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate.
Synonyms:Polypeptide N-acetylgalactosaminyltransferase 15 (EC 2.4.1.41) (Polypeptide GalNAc transferase-like protein 2) (GalNAc-T-like protein 2) (pp-GaNTase-like protein 2) (Polypeptide N-acetylgalactosaminyltransferase-like protein 2) (Protein-UDP acetylgalactosaminyltransferase-like protein 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2), GALNT15, GALNTL2
UniProt Protein Function:GALNTL2: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.Protein type: Vesicle; Membrane protein, integral; EC 2.4.1.41; Glycan Metabolism - O-glycan biosynthesis; TransferaseChromosomal Location of Human Ortholog: 3p25.1Cellular Component: Golgi membrane; integral to membrane; transport vesicleMolecular Function: carbohydrate binding; metal ion binding; polypeptide N-acetylgalactosaminyltransferase activityBiological Process: cellular protein metabolic process; O-glycan processing; post-translational protein modification; protein amino acid O-linked glycosylation
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8N3T1
NCBI GenInfo Identifier:190014583
NCBI Gene ID:117248
NCBI Accession:NP_473451.3
UniProt Secondary Accession:Q8N3T1,Q86T60, Q96C46, Q96DJ5, A6NMN1, B2R638, F1LIP6
UniProt Related Accession:Q8N3T1
Molecular Weight:
NCBI Full Name:polypeptide N-acetylgalactosaminyltransferase 15 isoform 1
NCBI Synonym Full Names:polypeptide N-acetylgalactosaminyltransferase 15
NCBI Official Symbol:GALNT15  
NCBI Official Synonym Symbols:PIH5; GALNT7; GALNT13; GALNTL2; GALNACT15; pp-GalNAc-T15  
NCBI Protein Information:polypeptide N-acetylgalactosaminyltransferase 15
UniProt Protein Name:Polypeptide N-acetylgalactosaminyltransferase 15
UniProt Synonym Protein Names:Polypeptide GalNAc transferase-like protein 2; GalNAc-T-like protein 2; pp-GaNTase-like protein 2; Polypeptide N-acetylgalactosaminyltransferase-like protein 2; Protein-UDP acetylgalactosaminyltransferase-like protein 2; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2
Protein Family:Polypeptide N-acetylgalactosaminyltransferase
UniProt Gene Name:GALNT15  
UniProt Entry Name:GLT15_HUMAN
Antibodies
GALNT15 Antibody (PACO09405)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
Recommended Products
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011)
Anti-HRP-conjugated Beta Actin Antibody (CABC028)

Related Products