The GALNT15 Polyclonal Antibody (PACO09405), provided by Assay Genie, is a valuable tool for researchers studying GALNT15, a glycosyltransferase enzyme involved in protein glycosylation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.GALNT15 plays a crucial role in the glycosylation process, which is essential for the modification of proteins and their functions within the cell. Dysregulation of glycosylation has been linked to various diseases, including cancer and neurodegenerative disorders, making GALNT15 a potential target for therapeutic interventions.
By utilizing the GALNT15 Polyclonal Antibody, researchers can investigate the expression and function of GALNT15 in different cell types and tissues, leading to a better understanding of its role in disease pathology. This antibody is a valuable tool for studies in glycobiology, cancer research, and other fields where protein glycosylation is a key factor.
GALNTL2: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.Protein type: Vesicle; Membrane protein, integral; EC 2.4.1.41; Glycan Metabolism - O-glycan biosynthesis; TransferaseChromosomal Location of Human Ortholog: 3p25.1Cellular Component: Golgi membrane; integral to membrane; transport vesicleMolecular Function: carbohydrate binding; metal ion binding; polypeptide N-acetylgalactosaminyltransferase activityBiological Process: cellular protein metabolic process; O-glycan processing; post-translational protein modification; protein amino acid O-linked glycosylation
PIH5; GALNT7; GALNT13; GALNTL2; GALNACT15; pp-GalNAc-T15Â Â
NCBI Protein Information:
polypeptide N-acetylgalactosaminyltransferase 15
UniProt Protein Name:
Polypeptide N-acetylgalactosaminyltransferase 15
UniProt Synonym Protein Names:
Polypeptide GalNAc transferase-like protein 2; GalNAc-T-like protein 2; pp-GaNTase-like protein 2; Polypeptide N-acetylgalactosaminyltransferase-like protein 2; Protein-UDP acetylgalactosaminyltransferase-like protein 2; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2
