GALNS Rabbit Polyclonal Antibody (CAB5461)
- SKU:
- CAB5461
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | GALNS Rabbit Polyclonal Antibody |
SKU: | CAB5461 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 353-522 of human GALNS (NP_000503.1). |
Sequence: | AGLT PPSD RAID GLNL LPTL LQGR LMDR PIFY YRGD TLMA ATLG QHKA HFWT WTNS WENF RQGI DFCP GQNV SGVT THNL EDHT KLPL IFHL GRDP GERF PLSF ASAE YQEA LSRI TSVV QQHQ EALV PAQP QLNV CNWA VMNW APPG CEKL GKCL TPPE SIPK KCLW SH |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | GAS; MPS4A; GalN6S; GALNAC6S; GALNS |
Positive Sample: | MCF7,HT-29,293T,Mouse kidney,Mouse brain,Mouse intestine |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome. |
Calculated MW: | 58kDa |
Observed MW: | 55kDa |
This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.
Purification Method: | Affinity purification |
Gene ID: | 2588 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |