The Galectin-3 Rabbit Monoclonal Antibody is a powerful tool for researchers studying Galectin-3, a multifunctional protein involved in various biological processes. This antibody, produced in rabbits, exhibits high reactivity with Galectin-3 in human samples and has been validated for use in Western blot applications. It specifically targets Galectin-3, allowing for precise detection and analysis in a variety of cell types, making it an excellent choice for studies in immunology, cancer research, and other fields.Galectin-3 is known for its roles in cell adhesion, proliferation, apoptosis, and inflammation, and dysregulation of its expression has been implicated in various diseases, including cancer, fibrosis, and cardiovascular disorders.
By studying Galectin-3 with this antibody, researchers can gain valuable insights into its functions and potential therapeutic applications in these disease contexts.Overall, the Galectin-3 Rabbit Monoclonal Antibody is a valuable tool for investigating the biology of Galectin-3 and its implications in health and disease. Its high specificity and sensitivity make it an essential component of any research program focused on understanding the complex roles of Galectin-3 in biological processes.
Product Name:
Galectin 3/LGALS3 Rabbit Monoclonal Antibody
SKU:
CAB11198
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Galectin 3/LGALS3 (P17931).
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix,the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis,innate immunity,cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3958
Clone Number:
ARC0542
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Galectin 3/LGALS3 Rabbit mAb (CAB11198) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
