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GALC Monoclonal Antibody (CAB23228)

SKU:
CAB23228
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
IF
$167 - $635
Frequently bought together:

Description

GALC Monoclonal Antibody (CAB23228)

The GALC Monoclonal Antibody (CAB23228) is a specialized tool for researchers investigating GALC, a critical enzyme involved in the breakdown of galactosylceramide. This monoclonal antibody, generated in mice, exhibits high specificity and sensitivity towards human GALC protein in various experimental applications, particularly in immunofluorescence and ELISA assays. By specifically targeting GALC, researchers can effectively study its role in lysosomal storage disorders and neurodegenerative diseases.GALC, also known as galactocerebrosidase, is essential for the metabolism of galactolipids in the nervous system, with mutations in the GALC gene leading to conditions like Krabbe disease.

Understanding the function and regulation of GALC is crucial for developing therapies to treat these disorders and improve patient outcomes. The GALC Monoclonal Antibody provides a reliable tool for investigating GALC expression and activity in both normal and diseased tissues, paving the way for innovative research in the field of neurology and rare genetic disorders.

Product Name:GALC Monoclonal Antibody
Product Code:CAB23228
Reactivity:Human
Applications:Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC58990
Reactivity:Human
Tested Applications:IF/ICC, ELISA
Key Applications:Immunofluorescence
Recommended Dilution:IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Cellular Location:Lysosome

This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Immunogen:Recombinant protein of human GALC.
Sequence:Email for sequence
Synonyms:GALC, galactocerebrosidase
Calculated MW:77kDa
Observed MW:Refer to figures

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