Galactosidase alpha (GLA) Rabbit Monoclonal Antibody (CAB5119)
- SKU:
- CAB5119
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Galactosidase alpha (GLA) Rabbit Monoclonal Antibody |
SKU: | CAB5119 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Galactosidase alpha (GLA) (GLA) (P06280). |
Sequence: | FMCN LDCQ EEPD SCIS EKLF MEMA ELMV SEGW KDAG YEYL CIDD CWMA PQRD SEGR LQAD PQRF PHGI RQLA NYVH SKGL KLGI YADV GNKT CAGF PGSF G |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | GALA; Galactosidase alpha (GLA) |
Positive Sample: | Raji,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome |
Calculated MW: | 49kDa |
Observed MW: | 49kDa |
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
Purification Method: | Affinity purification |
Gene ID: | 2717 |
Clone Number: | ARC1213 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |