The Gag Polyclonal Antibody (PACO33552) is a valuable tool for researchers studying Gag proteins in retrovirus replication. This antibody, produced against Gag protein in rabbits, shows high specificity and reactivity with human samples, making it ideal for use in Western blot and immunohistochemistry applications. Gag proteins play a crucial role in the assembly and release of retroviruses, making them important targets for understanding viral replication and pathogenesis. By targeting the Gag protein, researchers can study the mechanisms underlying viral assembly, budding, and maturation, providing insights into potential therapeutic strategies for combating retroviral infections.
With its high specificity and validated performance in various research applications, the Gag Polyclonal Antibody (PACO33552) is a valuable tool for researchers in virology, infectious diseases, and molecular biology. Its use in studying retrovirus replication can lead to advancements in the development of antiviral therapies and vaccines.
Antibody Name:
gag Antibody (PACO33552)
Antibody SKU:
PACO33552
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human immunodeficiency virus type 1 group M subtype B
Immunogen:
Recombinant Human immunodeficiency virus type 1 group M subtype B Gag polyprotein protein (2-132AA)
Gag polyprotein: Mediates, with Gag-Pol polyrotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi).1 Publication Matrix protein p17: Targets the polyprotein to the plasma membrane via a multipartite membrane-binding signal, that includes its myristoylated N-terminus (By similarity). Matrix protein is part of the pre-integration complex. Implicated in the release from host cell mediated by Vpu. Binds to RNA (By similarity).
Synonyms:
Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Spacer peptide 2 (SP2) (p1); p6-gag], gag
UniProt Protein Function:
Gag polyprotein: Mediates, with Gag-Pol polyrotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi).
