GADD45A Rabbit Polyclonal Antibody (CAB1797)
- SKU:
- CAB1797
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | GADD45A Rabbit Polyclonal Antibody |
SKU: | CAB1797 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-165 of human GADD45A (NP_001915.1). |
Sequence: | MTLE EFSA GEQK TERM DKVG DALE EVLS KALS QRTI TVGV YEAA KLLN VDPD NVVL CLLA ADED DDRD VALQ IHFT LIQA FCCE NDIN ILRV SNPG RLAE LLLL ETDA GPAA SEGA EQPP DLHC VLVT NPHS SQWK DPAL SQLI CFCR ESRY MDQW VPVI NLPE R |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | DDIT1; GADD45; GADD45A |
Positive Sample: | HeLa,293T,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 18kDa |
Observed MW: | 18kDa |
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1647 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |