The GABRR1 Polyclonal Antibody (CAB2937) is a valuable tool for researchers studying GABRR1, a subunit of the GABAA receptor known for its role in inhibitory neurotransmission in the brain. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the GABRR1 protein, this antibody enables the detection and analysis of GABAA receptor subunit expression in various cell types.GABRR1 is essential for the function of the GABAA receptor, which plays a crucial role in regulating neuronal excitability and neurotransmission. Dysregulation of GABAA receptor activity has been implicated in a variety of neurological disorders, including epilepsy, anxiety, and insomnia.
The GABRR1 Polyclonal Antibody offers researchers a reliable tool for investigating the expression and function of this important receptor subunit in both normal and pathological conditions.Overall, the GABRR1 Polyclonal Antibody is a valuable resource for studies in neuroscience and pharmacology, providing insights into the role of GABAA receptors in health and disease. Its specificity and sensitivity make it an ideal choice for researchers looking to further understand the complex mechanisms underlying inhibitory neurotransmission in the brain.
Product Name:
GABRR1 Rabbit Polyclonal Antibody
SKU:
CAB2937
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human GABRR1 (NP_002033.2).
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2569
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GABRR1 Rabbit pAb (CAB2937) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
