GABRD Rabbit Polyclonal Antibody (CAB16016)
- SKU:
- CAB16016
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | GABRD Rabbit Polyclonal Antibody |
SKU: | CAB16016 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-248 of human GABRD (NP_000806.2)). |
Sequence: | YVGS NLEI SWLP NLDG LIAG YARN FRPG IGGP PVNV ALAL EVAS IDHI SEAN MEYT MTVF LHQS WRDS RLSY NHTN ETLG LDSR FVDK LWLP DTFI VNAK SAWF HDVT VENK LIRL QPDG VILY SIRI TSTV ACDM DLAK YPMD EQEC MLDL ESYG YSSE DIVY YWSE SQEH IHGL DKLQ LAQF TITS YRFT TELM NFKS AGQF PRLS LHFH LRRN RG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | EJM7; EIG10; GEFSP5; GABRD |
Positive Sample: | MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | axon, dendrite, GABA-ergic synapse, neuron projection, plasma membrane, postsynaptic membrane, synapse |
Calculated MW: | 51kDa |
Observed MW: | 51kDa |
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 2563 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |