GABA A Receptor beta 2 (GABRB2) Rabbit Polyclonal Antibody (CAB1876)
The GABRB2 Polyclonal Antibody (CAB1876) is a valuable tool for researchers studying GABRB2, a gene encoding a gamma-aminobutyric acid (GABA) receptor subunit. This antibody, produced in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples. By binding to the GABRB2 protein, this antibody enables the detection and analysis of GABRB2 in various cell types, making it ideal for research in neuroscience and neurology.GABRB2 is a key player in the central nervous system, where it is involved in mediating the inhibitory effects of GABA, the major inhibitory neurotransmitter in the brain.
Dysregulation of GABRB2 has been implicated in various neurological disorders, including epilepsy, autism, and schizophrenia. Therefore, studying the function and expression of GABRB2 is crucial for understanding the pathophysiology of these conditions and developing potential therapies.Overall, the GABRB2 Polyclonal Antibody (CAB1876) is a reliable tool for researchers aiming to explore the role of GABRB2 in neurological disorders and advance our understanding of GABAergic signaling in the brain.
Product Name:
GABA A Receptor beta 2 (GABRB2) Rabbit Polyclonal Antibody
SKU:
CAB1876
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-244 of human GABA A Receptor beta 2 (GABA A Receptor beta 2 (GABRB2)) (NP_000804.1).
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion.
Purification Method:
Affinity purification
Gene ID:
2561
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using GABA A Receptor beta 2 (GABA A Receptor beta 2 (GABRB2)) Rabbit pAb (CAB1876) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
