GABA A Receptor beta 1 (GABRB1) Rabbit Polyclonal Antibody (CAB16015)
The GABRB1 Polyclonal Antibody (CAB16015) is a valuable tool for researchers studying the GABRB1 protein, a key component of the GABA-A receptor, which plays a crucial role in neurotransmission and brain function. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting and immunohistochemistry applications.GABRB1 is a subunit of the GABA-A receptor, which is involved in the regulation of neuronal excitability and synaptic transmission. Dysregulation of GABA-A receptors has been implicated in various neurological disorders, including epilepsy, anxiety disorders, and schizophrenia.
By targeting GABRB1, researchers can gain insight into the function and dysfunction of the GABAergic system, paving the way for the development of novel therapeutic strategies for these conditions.With its high specificity and sensitivity, the GABRB1 Polyclonal Antibody (CAB16015) is an essential tool for investigating the role of the GABRB1 protein in health and disease. Whether studying normal brain function or exploring potential therapeutic targets, this antibody is a valuable resource for researchers in neuroscience and pharmacology.
Product Name:
GABA A Receptor beta 1 (GABRB1) Rabbit Polyclonal Antibody
SKU:
CAB16015
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human GABA A Receptor beta 1 (GABRB1) (NP_000803.2).
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.
Purification Method:
Affinity purification
Gene ID:
2560
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GABA A Receptor beta 1 (GABRB1) Rabbit pAb (CAB16015) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
