The Gabra5 Polyclonal Antibody (CAB13984) is an essential tool for researchers studying Gabra5, a key component of the GABA-A receptor complex involved in neurotransmission and neurological disorders. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting.Gabra5 is a subunit of the GABA-A receptor, which plays a crucial role in inhibitory neurotransmission in the central nervous system. Dysregulation of this receptor has been implicated in various neurological disorders, such as epilepsy, anxiety, and sleep disorders.
The Gabra5 Polyclonal Antibody binds specifically to the Gabra5 protein, allowing for precise detection and analysis in different cell types.Research on Gabra5 is essential for understanding the mechanisms underlying neurological disorders and developing targeted therapies. The Gabra5 Polyclonal Antibody is a valuable tool for investigating the function and regulation of Gabra5, making it an ideal choice for studies in neuroscience and drug development.
Product Name:
GABRA5 Rabbit Polyclonal Antibody
SKU:
CAB13984
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 32-259 of human GABRA5 (NP_000801.1).
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.
Purification Method:
Affinity purification
Gene ID:
2558
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of rat skeletal muscle, using GABRA5 antibody (CAB13984) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
