GABRA1 Rabbit Polyclonal Antibody (CAB12244)
- SKU:
- CAB12244
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | GABRA1 Rabbit Polyclonal Antibody |
SKU: | CAB12244 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-251 of human GABRA1 (NP_000797.2). |
Sequence: | QPSL QDEL KDNT TVFT RILD RLLD GYDN RLRP GLGE RVTE VKTD IFVT SFGP VSDH DMEY TIDV FFRQ SWKD ERLK FKGP MTVL RLNN LMAS KIWT PDTF FHNG KKSV AHNM TMPN KLLR ITED GTLL YTMR LTVR AECP MHLE DFPM DAHA CPLK FGSY AYTR AEVV YEWT REPA RSVV VAED GSRL NQYD LLGQ TVDS GIVQ SSTG EYVV MTTH FHLK RKIG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | EJM; ECA4; EJM5; DEE19; EIEE19; GABRA1 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2554 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |