The GABPB1 Polyclonal Antibody (CAB6909) is designed for research involving GABPB1, a transcription factor that plays a key role in regulating gene expression. The antibody, raised in rabbits, is highly specific and reactive with human, mouse, and rat samples, making it versatile for use in various experimental settings.GABPB1 is known to be involved in the transcriptional regulation of genes associated with cell proliferation, differentiation, and apoptosis. Its importance in controlling gene expression makes it a valuable tool for studying cellular processes in development, cancer, and other diseases.
By targeting GABPB1 with this antibody, researchers can investigate its role in gene regulation and its potential as a therapeutic target.With its high specificity and reactivity across multiple species, the GABPB1 Polyclonal Antibody is a reliable tool for researchers studying transcriptional regulation and its impact on cellular function. Whether used in Western blot or immunofluorescence applications, this antibody enables accurate detection and analysis of GABPB1 protein levels, contributing to a better understanding of its function in various biological contexts.
Product Name:
GABPB1 Rabbit Polyclonal Antibody
SKU:
CAB6909
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 231-395 of human GABPB1 (NP_005245.2).
This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
2553
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of MCF7, using GABPB1 antibody (CAB6909) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
