GABPA Rabbit Polyclonal Antibody (CAB8419)
- SKU:
- CAB8419
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | GABPA Rabbit Polyclonal Antibody |
SKU: | CAB8419 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GABPA (NP_002031.2). |
Sequence: | MTKR EAEE LIEI EIDG TEKA ECTE ESIV EQTY APAE CVSQ AIDI NEPI GNLK KLLE PRLQ CSLD AHEI CLQD IQLD PERS LFDQ GVKT DGTV QLSV QVIS YQGI EPKL NILE IVKP ADTV EVVI DPDA HHAE SEAH LVEE AQVI TLDG TKHI TTIS DETS EQVT RWAA ALEG YRKE QERL GIPY DPIQ WSTD QVLH WVVW VMKE FSMT DIDL TTLN ISGR ELCS LNQE DFFQ RVPR GEIL WSHL ELLR KYVL ASQE QQMN |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | NFT2; NRF2; NRF2A; E4TF1A; E4TF1-60; RCH04A07; GABPA |
Positive Sample: | SW480,HT-1080,Mouse heart,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 51kDa |
Observed MW: | 56kDa |
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2551 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |