The Gabpa Polyclonal Antibody (CAB8419) is a valuable tool for researchers studying the transcription factor Gabpa, which plays a crucial role in gene regulation and cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications, allowing for the detection and analysis of Gabpa protein levels in various cell types.Gabpa, also known as GA-binding protein alpha chain, is involved in regulating gene expression related to cell growth, differentiation, and apoptosis. Its function in controlling transcription makes it a key player in processes such as immune response, cell proliferation, and development.
Researchers studying cancer biology, neurobiology, and developmental biology can benefit from using this antibody to explore the role of Gabpa in these contexts.The Gabpa Polyclonal Antibody can provide valuable insights into the mechanisms underlying Gabpa's function and its impact on cellular processes. By understanding the role of Gabpa in gene regulation and transcriptional control, researchers can identify potential therapeutic targets for diseases such as cancer, neurodegenerative disorders, and developmental abnormalities. This antibody is a reliable tool for investigating the intricate pathways involving Gabpa and its implications in various biological processes.
Product Name:
GABPA Rabbit Polyclonal Antibody
SKU:
CAB8419
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GABPA (NP_002031.2).
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2551
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GABPA Rabbit pAb (CAB8419) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
