GABPA Rabbit Polyclonal Antibody (CAB12047)
- SKU:
- CAB12047
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | GABPA Rabbit Polyclonal Antibody |
SKU: | CAB12047 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GABPA (NP_002031.2). |
Sequence: | NLKK LLEP RLQC SLDA HEIC LQDI QLDP ERSL FDQG VKTD GTVQ LSVQ VISY QGIE PKLN ILEI VKPA DTVE VVID PDAH HAES EAHL VEEA QVIT LDGT K |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | NFT2; NRF2; NRF2A; E4TF1A; E4TF1-60; RCH04A07; GABPA |
Positive Sample: | HeLa,Raji,HepG2,SKOV3,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 51kDa |
Observed MW: | 60kDa |
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2551 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |