The GABPA Polyclonal Antibody (CAB12047) is a valuable tool for researchers studying the GABPA protein, a transcription factor involved in regulating gene expression and cell growth. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the GABPA protein, researchers can detect and analyze its presence in various cell types, making it ideal for studies in molecular biology and cancer research.GABPA plays a critical role in controlling gene transcription, cell proliferation, and differentiation, making it a key player in various cellular processes.
Its involvement in cancer progression and other diseases makes it a promising target for drug development and therapeutic interventions. By studying the function of GABPA, researchers can deepen their understanding of disease mechanisms and potentially uncover new treatment strategies.Overall, the GABPA Polyclonal Antibody (CAB12047) is a valuable tool for researchers interested in exploring the role of GABPA in cellular function and disease pathogenesis. Its specificity, sensitivity, and reliability make it an essential reagent for any laboratory conducting research in the fields of molecular biology and cancer biology.
Product Name:
GABPA Rabbit Polyclonal Antibody
SKU:
CAB12047
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GABPA (NP_002031.2).
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2551
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GABPA Rabbit pAb (CAB12047) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
