The GABARAPL2 Polyclonal Antibody (CAB14855) is a valuable tool for researchers studying GABARAPL2, a protein involved in autophagy, a cellular process that degrades and recycles unnecessary or dysfunctional components. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications.GABARAPL2 is a member of the Atg8 protein family, which plays a crucial role in autophagosome formation and autophagic cargo recruitment. Dysregulation of autophagy has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic conditions.
Therefore, studying the function and regulation of GABARAPL2 is essential for understanding the role of autophagy in these pathological processes.By targeting GABARAPL2, researchers can investigate the molecular mechanisms underlying autophagy and its impact on disease progression. The GABARAPL2 Polyclonal Antibody offers a reliable tool for detecting and analyzing GABARAPL2 expression in different cell types, making it suitable for applications in cell biology, cancer research, and drug development related to autophagy modulation.
Product Name:
GABARAPL2 Rabbit Polyclonal Antibody
SKU:
CAB14855
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-50 of human GABARAPL2 (NP_009216.1).
Enables ubiquitin protein ligase binding activity. Involved in negative regulation of proteasomal protein catabolic process and protein localization to endoplasmic reticulum. Located in Golgi membrane and autophagosome membrane.
Purification Method:
Affinity purification
Gene ID:
11345
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GABARAPL2 Rabbit pAb (CAB14855) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
